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Simple blood test may reveal your body’s inner clock

By AFP - Sep 11,2018 - Last updated at Sep 11,2018

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WASHINGTON — Ever feel like it’s 7am, even though the clock says 9am?

A team of researchers at Northwestern University said on Monday they have designed a blood test that can measure a person’s inner body clock within 1.5 hours, an advance that may help personalise medical treatments in the future.

The study was published in the Proceedings of the National Academy of Sciences (PNAS), a peer-reviewed US journal.

The “circadian rhythm” governs all cells in the body and is a burgeoning field of research.

This biological clock regulates “all sorts of biological processes, when you feel sleepy, when you feel hungry, when your immune system is active, when your blood pressure is high, when your body temp changes”, said lead author Rosemary Braun, assistant professor of biostatistics at Northwestern University.

When the clock is not regulated properly, research has shown a link to diseases like Alzheimer’s, heart problems and diabetes.

Other research has pointed to the possibility some medical interventions like chemotherapy or blood pressure drugs might be more effective if taken at a certain time.

For the study, researchers took more than 1,100 blood samples from 73 people.

Samples were taken every two hours and gene activity was tested at each interval to see how it changed over the day.

The research allowed scientists to decipher if a person’s body clock was off, for example, by up to two hours.

All the data from the 73 people studied was computerised, and it revealed a pattern.

“What the algorithm told us, is that there were a small set of about 40 markers that could predict the time of day with great accuracy,” said Braun.

Using this algorithm, scientists only need to take two blood draws to have enough information to decipher person’s body clock.

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